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LGD-4033 boasts high selectivity when it bonds to androgen-receptive cells in the body, opting for those in muscles and bones, a study has found.
The team, which includes scientists from the University of North Carolina at Chapel Hill and the Department of Pharmacology at the Karolinska Institute in Sweden, found THC in the blood of mice injected with THC, sarms ligandrol uk. THC is the psychoactive component of "marihuana", the recreational drug currently used by some Canadians to treat nausea and other ill effects from the Mexican herb.
Previous research had shown that THC acts on the body's cannabinoid receptors, a type of molecule that responds to changes in the tone of the neurotransmitter endocannabinoid system – including the one in the brain's nerve cells, which are responsible for controlling feelings of alertness or relaxation, sarms lgd 4033 uk.
"The goal is to develop drugs that can be used by humans and animals alike, so that we can use the body's own cannabinoid receptors to regulate how much THC is absorbed into the bloodstream," said study co-author Mark Wareham, senior investigator at the UNC-CH Center for Medicinal Chemistry and Pharmacology.
The UNC project was funded by the Health Canada Center for Medicinal Research, the Swedish Research Council and the European Community's Seventh Framework Programme (FP7/2007-2013) under the European Neighbourhood Program, lgd 4033 cycle for bulking.
The research team was able to identify THC by analyzing the THC level in blood of mice, as opposed to other body tissues, lgd-4033 review uk. The THC level is highly dependent on the species tested, with some mammalian species showing the highest levels.
"These results also show we've actually identified one of the few molecules in natural systems that can bind and alter the function of these cannabinoid receptors, lgd 4033 uk buy. There is still much to discover as to which proteins and receptors carry out these functions," Wareham said.
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The findings were published today (June 12) online in the journal Nature Communications, oral steroid cycle for bulking.
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